Coronary Artery CT Scans & Cancer Risk

It has been estimated by experts that up to 2 percentthese otherwise preventable cancers would manifest
of all cancer cases are caused by exposure toas leukemia in women.
medical x-ray tests. Although it is believed that there isUnfortunately, there is currently no scientific consensus
no completely safe level of exposure to x-rays, it isregarding the clinical benefit, if any, of using CT
well known that exposure to increasing doses ofscanners to detect coronary artery disease in
x-rays, as well as undergoing repeated x-rayasymptomatic patients, as there is no high level clinical
examinations, increases the risk of cancer formation.research data available to prove that this screening
The increasing use of CT scanners (which canapproach reduces cardiac disease events, or
expose patients to significant doses of radiation) tocardiac-associated deaths. Therefore, all that can be
screen asymptomatic patients for coronary arteryconfidently said, at this time, about the routine use of
disease has been a source of growing concernCT scans to screen for coronary artery disease is
among many cancer experts. While the detection ofthat it is, undoubtedly, associated with a small but not
coronary artery calcifications and coronary arteryinsignificant risk of otherwise preventable cancers.
narrowing (stenosis) on multi-detector CT scannersMoreover, when you consider that the authors of this
are powerful predictors of future cardiac diseasestudy used very conservative estimates regarding
events, it remains unclear, at this time, whether or notabsorbed radiation doses in patients undergoing
this approach to coronary artery disease screeningcoronary artery screening, the actual cancer risk
offers any significant clinical benefits to otherwiseassociated with many of cardiac screening CT scan
asymptomatic patients.protocols in current use is probably significantly higher
A newly published clinical research study, whichthan what this study predicts.
appears in the current issue of the Annals of InternalIn my own case, I underwent two separate CT scans,
Medicine, further quantifies the potential cancer riskto assess for both coronary artery calcifications and
associated with the use CT scans to screen forcoronary artery narrowing (stenosis), as part of a "VIP
coronary artery disease.Physical" in 2006. At the time, there was great
Because there are no nationally standardized protocolsenthusiasm for the routine use of CT scanners for this
for CT scan cardiac screening examinations, thepurpose. However, based upon the available data
authors of this study considered several commonly(including the data from this study), I have recently
used CT scan protocols, and then calculated the actualdecided that I will not undergo any additional heart
dose of radiation delivered to patients with each ofscreening CT scans until and unless compelling clinical
these scan protocols. Using long-term data deriveddata comes along to suggest that the benefit from
from Japanese atomic bomb survivors, thesuch scans outweighs their potential risks. If you have
researchers then estimated the added cancer risk tobeen considering undergoing a routine cardiac
patients receiving coronary artery screening CT scans.screening CT scan, my advice is to first discuss the
One important (and concerning) finding from this studydata contained in this clinical study with your Internist or
is that radiation doses delivered to patients vary byCardiologist, and ask them to clarify both the potential
more than 10-fold among the different CT scanrisks and benefits, in your particular case, of undergoing
protocols in common use throughout the United States.a coronary artery screening CT scan.
Based upon existing screening recommendations, theMeanwhile more research is needed to clarify what, if
authors calculated the added cancer risk associatedany, health benefits can be reasonably claimed for
with adult patients undergoing coronary arteryroutine coronary artery screening CT scans in
screening CT scans every 5 years between the agesasymptomatic patients. Finally, in view of the immense
of 45 and 75 years for men, and every 5 yearsvariation in radiation doses associated with the various
between the ages of 55 and 75 years for women.CT scanning protocols in common use today,
Using the very conservative assumption that allprofessional radiology societies and boards should
patients are exposed to a dose of radiation equivalentquickly work to reach a consensus on standardizing
to the average of all commonly used CT scanthese protocols in such a way that unnecessary
protocols, the authors calculated that the lifetimeradiation exposure is minimized.
increased incidence of cancer was 4.2 new cases ofBy, Robert A. Wascher, MD, FACS
cancer per 10,000 men, and 6.2 new cases of cancerUpdated: 07/26/2009
per 10,000 women. Based upon the known effects of____
radiation to the organs contained in the chest area,The information in this column is intended for
approximately 71 percent of the cancer cases causedinformational purposes only, and does not constitute
by CT scans of the heart would be in the form of lungmedical advice or recommendations by the author.
cancer, while 20 percent of these "excess" cancersPlease consult with your physician before making any
would be breast cancers induced in women. Anotherlifestyle or medication changes, or if you have any
12 percent of these radiation-induced cancers wouldother concerns regarding your health.
be in the form of leukemia in men, while 4 percent of