Mesothelioma Diagnosis-What Are the 3 Different Types of Biopsy That Can be Used?

helioma is a very rare form of asbestos relatedare close to the skin's surface, needle aspiration biopsy
cancer that is most effectively treated when detected(also called fine needle aspiration cytology or fine
early. Unfortunately, the nature of the disease and theneedle aspiration) can also be used to diagnose
fact that it remains latent for decades usually results inmesothelioma. Essentially, this technique uses a long,
late detection after the cancer has spread to otherhollow needle to remove a sample of cells from the
parts of the body, making it extremely difficult to treat.body to be tested and properly diagnosed. When this
One method used in the detection/diagnosis ofmethod is used to collect samples in mesothelioma
mesothelioma is a surgical biopsy.cancer, the surgeon makes use of certain equipments
There are three different types of biopsies availablethat help him guide the needle carefully to where the
for those who have developed mesothelioma. Biopsytumor is located. After the cells are removed from the
involves the surgeon removing the tissue in questionbody, a pathologist who is a doctor that specializes in
for laboratory examination. Three types of biopsy are:diagnosing diseases using cellular structures examines
1- Incisional biopsy or a core biopsythe cells under a microscope to determine the
In this type of biopsy only a small part of the tissue isdiagnosis. The pathologist employs a number of
removed. This type of biopsy is used most commonlydifferent techniques to diagnose the cells after biopsy,
when the tumor is located in an area that is easilybut in most cases the pathologist removes a very thin
reached for example in breast cancer, however inlayer of tissue from the sample, places it on a
most cases of mesothelioma especially in the pleuralmicroscope slide, adds dye to make cells more visible,
and peritoneal form of the disease the tumor is notand seals the slide so it can be examined under a
easily accessible. So this type of biopsy has verymicroscope.
limited use in the diagnosis of mesothelioma.A pathologist is trained to analyze abnormal cell
2- Excisional biopsygrowth, which can indicate mesothelioma as well as
In Excisional biopsy the whole tumor mass is removedother diseases. Other techniques employed by the
by the surgeon as compared to incisional biopsy inpathologist involves the use of biochemical specialized
which just a small portion of the tumor mass isstaining procedures to identify specific tumor markers
removed. Excisional biopsy naturally comes withon the cancer cells.
greater risks. Surgery is more extensive and timeBiopsy also allows the pathologist to examine the
consuming it is also more complicated and the surgeonpossible spread of cancer to other parts of the body.
end up removing a significant portion of the sensitiveWhen the tumors in the body are removed, the
linings surrounding major organs. However, it is alwayspathologist carefully examines the margins to see if
better to operate once very extensively than to makecancer is present. "Negative margins" means the
the patient undergo the same operation twice oncecancer has probably not spread; the appearance of
the laboratory tests on the tissue samples confirm the"positive margins" means there is a good chance that
cancer.the cancer has spread beyond that tumor mass the
3- Fine needle aspiration biopsysurgeon removed. Mesothelioma spreads quickly, so if
The third type of diagnostic biopsy is called needlethe biopsy report indicates the presence of possible
aspiration biopsy. In many cases, this is the techniquemetastases, additional imaging tests like CTscans,
most preferred by surgeons because it is a safe, quickX-rays, MRIscans, PET scans are used to locate the
procedure. Although most often used for tumors thatextent of spread.